Table 2.
Composition and Observed Responses from Randomized Runs in Formulation Screening
| Composition (%, m/m) EO: Tween 80: PEG400 |
100 Times Dilution | |||||
|---|---|---|---|---|---|---|
| Size(nm) | PDI | ζ Potential | Emulsification Time | Appearance | ||
| F1 | 1:6:3 | 12.0 ± 0.17 | 0.09 ± 0.01 | −6.61± 0.69 | < 1 min | Transparent |
| F2 | 2:7:1 | 77.59 ± 1.58 | 0.28 ± 0.01 | −13.40 ± 1.26 | < 1 min | Transparent |
| F3 | 2:5:3 | 15.77 ± 0.74 | 0.18 ± 0.05 | −10.55 ± 2.12 | <1 min | Light blue |
| F4 | 3:5:2 | 21.14 ± 0.48 | 0.12 ± 0.02 | −10.06 ± 1.32 | <1 min | Blue |
| F5 | 3:4:3 | 86.64 ± 1.98 | 0.30 ± 0.01 | −5.98 ± 1.75 | < 2 min | Light blue |
| F6 | 3:6:1 | 19.81 ± 0.21 | 0.10 ± 0.01 | −11.64 ± 0.46 | < 1 min | Blue |
| F7 | 3:7:7 | 15.45 ± 0.09 | 0.12 ± 0.01 | −8.49 ± 0.86 | < 1 min | Light blue |
| F8 | 6:14:7 | 17.01 ± 0.29 | 0.12 ± 0.01 | −9.16 ± 1.65 | <3 min | white-blue |
| F9 | 9:21:7 | 18.01 ± 0.56 | 0.12 ± 0.01 | −9.74 ± 0.92 | <1 min | Light blue |