Table 6.
Correlation of TNF-α Promoter Polymorphism with Patient Clinical Characteristics
| Variables | TNF-α Promoter Polymorphism | p-value | ||
|---|---|---|---|---|
| G/G | G/A | A/A | ||
| Age (years) | ||||
| Mean ±SD | 34.5± 7.0 | 24.5 ± 8.0 | 19.0±9 | 0.8 |
| Onset of the disease | 22.22 ± 12.98 | 21.29 ± 12.80 | 19.46 ± 12.69 | 0.79 |
| Gender | ||||
| Males | 13 | 6 | 4 | 0.97 |
| Female | 34 | 14 | 9 | |
| Family history of vitiligo | ||||
| Positive | 20 (43.5%) | 9 (42.9%) | 9 (69.2%) | 0.23 |
| Negative | 26 (56.5%) | 12 (57.1%) | 4 (30.8%) | |
| VIDA score | ||||
| −1 | 4 (8.9%) | 1 (4.8%) | 2 (15.4%) | 0.66 |
| 0 | 5 (11.1%) | 4 (19%) | 2 (15.4%) | |
| 1 | 20 (44.4%) | 11 (52.4%) | 4 (30.8%) | |
| 2 | 9 (20%) | 2 (9.5%) | 2 (15.4%) | |
| 3 | 2 (4.4%) | 0 (0%) | 2 (15.4%) | |
| 4 | 5 (11.1%) | 3 (14.3%) | 1 (7.7%) | |
| VES score | ||||
| < 2 | 5 (11.1%) | 3 (14.3%) | 1 (7.7%) | 0.76 |
| 2–10 | 15 (32.6%) | 8 (38.1%) | 7 (53.8%) | |
| 10–20 | 6 (13%) | 3 (14.3%) | 2 (15.4%) | |
| > 20 | 4 (8.7%) | 3 (14.3%) | 1 (7.7%) | |