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. 2020 Nov 17;15(11):e0241853. doi: 10.1371/journal.pone.0241853

Table 2. Univariate analysis of the association between each factor and postoperative hydrocephalus.

Variables Postoperative CSF diversion P-value
Yes (15) No (106)
Sex 0.012a
    Female 3 (4.9%) 51 (95.1%)
    Male 12 (20%) 48 (80%)
Tumor size (mm) 40 (34–49) 36 (30–43) 0.100
Age (years) 18 (3–38) 24 (9–41) 0.301
Tumor pathology
    Ependymoma 3 (8.1%) 34 (91.9%) 0.226b c
    Medulloblastoma 5 (17.2%) 24 (82.8%) 1.0b c
    Astrocytoma 4 (20.0%) 16 (80.0%)
Lateral extension 0.553b
    Yes 3 (8.8%) 31 (91.2%)
    No 12 (13.8%) 75 (86.2%)
Anterior extension 0.159b
    Yes 88 (89.8%) 10 (10.2%)
    No 5 (21.7%) 18 (78.3%)
Caudal extension 0.420a
    Yes 10 (14.5%) 59 (85.5%)
    No 5 (9.6%) 47 (90.4%)
Superior extension 0.015b
    Yes 5 (35.7%) 9 (64.3%)
    No 10 (9.3%) 97 (90.7%)
Extent of resection <0.001b
    GTR 3 (3.3%) 87(96.7%)
    STR 12 (38.7%) 19(61.3%)
Preoperative hydrocephalus <0.001a
    Yes 15 (21.4%) 55 (78.6%)
    No 0 (0%) 51 (100%)
Prophylactic EVD 0.091a
    Yes 10 (17.9%) 46 (82.1%)
    No 5 (7.7%) 60 (92.3%)

CSF, cerebrospinal fluid; GTR, gross total resection; STR, subtotal resection; EVD, external ventricular drainage.

a Chi-square test.

b Fisher exact test.

c p value compared with astrocytoma.