Figure 7.

Gene expressions of iPSC–MSC trilineage differentiations. (a–f) qPCR showed an increased expression of (a, b) adipocyte-related genes (FABP4 and PPARγ), (c, d) osteocyte-related genes (osteopontin [OPN] and alkaline phosphatase [ALPL]), and (e, f) chondrocyte-related genes (type II collagen [COL2A1] and aggrecan [ACAN]) genes postdifferentiation. AM: adipogenesis medium; OM: osteogenesis medium; CM: chondrogenesis medium. ^∗∗p < 0.01, ^∗∗∗p < 0.001. The experiment was performed thrice. Statistical analyses between both groups were calculated with Mann–Whitney U test.