Table 1.
Top 10 up- and downregulated DEGs in GSE29111.
| Gene symbol | P value | LogFC | Gene function | PubMed IDs |
|---|---|---|---|---|
| Upregulated | ||||
| TSTA3 | 1.29E-05 | 1.0854319 | GDP-4-dehydro-D-rhamnose reductase activity | 11698403 |
| SLC22A11 | 2.64E-05 | 1.7937471 | Organic anion transmembrane transporter activity | 15102942 |
| ALDH5A1 | 3.94E-05 | 1.1577679 | Protein homodimerization activity | 16199352 |
| PLA2G16 | 5.57E-05 | 1.2325045 | Catalyzes the release of fatty acids from phospholipids in adipose tissue | 17374643 |
| DTNA | 7.35E-05 | 2.0915867 | Clustering of nicotinic acetylcholine receptors | 11353857 |
| HIF3A | 7.63E-05 | 1.4873978 | Adaptive response to hypoxia | 11573933 |
| POLL | 1.25E-04 | 1.3674519 | Repair polymerase | 10982892 |
| CTDSPL | 1.42E-04 | 2.1596408 | Negatively regulates RNA polymerase II transcription | 20379614 |
| ENDOV | 1.43E-04 | 1.6507937 | Cleaves inosine-containing RNAs | 23912683 |
| THSD4 | 1.49E-04 | 2.1230904 | Promotes FBN1 matrix assembly | 19734141 |
| Downregulated | ||||
| KYAT1 | 8.00E-06 | -2.1991848 | CCBL activity and transaminase activity with many amino acids | 19826765 |
| LOC101927044 | 1.48E-05 | -1.4311556 | Uncharacterized | — |
| ADAMTS9 | 1.58E-05 | -1.5421577 | Metallopeptidase activity | 12514189 |
| ETS1 | 2.41E-05 | -1.1693245 | Transcription factor binding | 10698492 |
| PNMA3 | 2.82E-05 | -1.4922227 | Nucleic acid binding | 16344560 |
| MARC2 | 4.20E-05 | -2.2687039 | Nitrate reductase activity | 20808825 |
| HSD17B12 | 4.54E-05 | -2.1426028 | Long fatty acid elongation | 20937905 |
| SCRT1 | 4.62E-05 | -1.489692 | Transcriptional repressor | 11274425 |
| PNMA6A | 6.01E-05 | -1.3616952 | Functional ribosomal frameshift signal | 16407312 |
| APOC1 | 8.06E-05 | -1.16521 | Fatty acid binding | 17339654 |