Proinflammatory cytokines in plasma of P. yoelii
yoelii 17XNL-infected and control mice. (A to I) The x axis represents the time points in days after infection, and the y axis represents the plasma concentrations of IL-6 (A), IL-18 (B), IFN-γ (C), IL-12p40 (D), TNF-α (E), IL-1β (F), IL-17 (G), IL-12p70 (H), and IL-2 (I). Each dot represents a single mouse. Data were analyzed with the Kruskal-Wallis test followed by Dunn’s multiple comparison of each time point with the control group. P values of <0.05 were considered significant. *, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001.