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. 2020 Nov 4;12:580068. doi: 10.3389/fnagi.2020.580068

Table 2.

Expression of P2X4R and IL-6 in the substantia nigra (SN) of rats in six groups.

Control 6-OHDA P2X4R-OE P2X4R-NC P2X4R-OE P2X4R-NC F P
+ 6-OHDA + 66-OHDA
n 10 10 10 10 10 10
P2X4R 0.8537 ± 0.0887 1.2620 ± 0.0260 1.4223 ± 0.1174 0.8425 ± 0.0737 1.8509 ± 0.1162 1.2095 ± 0.1056 163.647 <0.001
IL-6 0.7164 ± 0.0650 0.8855 ± 0.0734 0.7633 ± 0.0766 0.7390 ± 0.0572 1.2726 ± 0.0542 0.9020 ± 0.0638 100.051 <0.001

6-OHDA, 6-hydroxydopamine; P2X4R-OE, P2X4 receptor-overexpression; P2X4R-NC, P2X4 receptor-negative control; IL-6, interleukin-6.