Table 1.
Comparison between BMSCs, ADSCs, UC-MSCs and UCB-MSCs for stem cell therapy.
| Characteristic | BMSCs | ADSCs | UC-MSCs UCB-MSCs |
|---|---|---|---|
| Ethical conundrum | No | No | No |
| Tissue collection | Invasive | Invasive | None invasive (unwanted tissue after delivery) |
| Tissue processing and cell culture | Easy | Easy | Easy |
| Effect of donor age on cells | Quantity and quality decline with age | Quantity and quality decline with age | Unaffected |
| Cell proliferative potential | Lower | Lower | Higher |
| Expression of embryonic markers | Lower | Lower | Higher |
| Anti-inflammatory property | Good | Good | Good |
| Allogeneic cell rejection | No | No | No |
| Risk of tumor formation | Very low | Very low | Very low |
BMSCs, Bone marrow-derived mesenchymal stromal cells; ADSCs, adipose tissue-derived mesenchymal stromal cells; UC-MSCs, umbilical cord-derived mesenchymal stromal cells; UCB-MSCs, Umbilical cord blood-derived mesenchymal stromal cells.