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. 2020 Nov 4;8:591693. doi: 10.3389/fped.2020.591693

Table 1.

Comparison between BMSCs, ADSCs, UC-MSCs and UCB-MSCs for stem cell therapy.

Characteristic BMSCs ADSCs UC-MSCs UCB-MSCs
Ethical conundrum No No No
Tissue collection Invasive Invasive None invasive (unwanted tissue after delivery)
Tissue processing and cell culture Easy Easy Easy
Effect of donor age on cells Quantity and quality decline with age Quantity and quality decline with age Unaffected
Cell proliferative potential Lower Lower Higher
Expression of embryonic markers Lower Lower Higher
Anti-inflammatory property Good Good Good
Allogeneic cell rejection No No No
Risk of tumor formation Very low Very low Very low

BMSCs, Bone marrow-derived mesenchymal stromal cells; ADSCs, adipose tissue-derived mesenchymal stromal cells; UC-MSCs, umbilical cord-derived mesenchymal stromal cells; UCB-MSCs, Umbilical cord blood-derived mesenchymal stromal cells.