Table 4.
KEGG pathway enrichment analysis.
| ID | Description | P value | P.adjust | Q value | Count |
|---|---|---|---|---|---|
| hsa01521 | EGFR tyrosine kinase inhibitor resistance | 5.14E-22 | 8.28E-20 | 4.87E-20 | 40 |
| hsa04210 | Apoptosis | 1.89E-16 | 1.52E-14 | 8.95E-15 | 46 |
| hsa04066 | HIF-1 signaling pathway | 1.68E-13 | 8.77E-12 | 5.16E-12 | 37 |
| hsa04151 | PI3K-Akt signaling pathway | 2.18E-13 | 8.77E-12 | 5.16E-12 | 75 |
| hsa01522 | Endocrine resistance | 8.16E-13 | 2.63E-11 | 1.55E-11 | 34 |
| hsa01524 | Platinum drug resistance | 5.45E-12 | 1.46E-10 | 8.60E-11 | 28 |
| hsa04215 | Apoptosis - multiple species | 1.78E-10 | 4.09E-09 | 2.40E-09 | 17 |
| hsa04510 | Focal adhesion | 2.11E-10 | 4.24E-09 | 2.50E-09 | 47 |
| hsa04012 | ErbB signaling pathway | 3.62E-10 | 6.48E-09 | 3.82E-09 | 28 |
| hsa00910 | Nitrogen metabolism | 9.18E-10 | 1.48E-08 | 8.69E-09 | 12 |
| hsa04010 | MAPK signaling pathway | 1.16E-09 | 1.70E-08 | 1.00E-08 | 59 |
| hsa04015 | Rap1 signaling pathway | 1.45E-09 | 1.81E-08 | 1.07E-08 | 47 |
| hsa04068 | FoxO signaling pathway | 1.46E-09 | 1.81E-08 | 1.07E-08 | 35 |
| hsa04014 | Ras signaling pathway | 1.69E-09 | 1.94E-08 | 1.14E-08 | 50 |
| hsa04115 | p53 signaling pathway | 5.16E-09 | 5.54E-08 | 3.26E-08 | 24 |
| hsa04370 | VEGF signaling pathway | 1.26E-08 | 1.27E-07 | 7.46E-08 | 21 |
| hsa04071 | Sphingolipid signaling pathway | 9.42E-08 | 8.92E-07 | 5.25E-07 | 30 |
| hsa04213 | Longevity regulating pathway - multiple species | 9.21E-07 | 8.24E-06 | 4.85E-06 | 19 |
| hsa00140 | Steroid hormone biosynthesis | 2.52E-06 | 2.14E-05 | 1.26E-05 | 18 |
| hsa04152 | AMPK signaling pathway | 4.54E-06 | 3.66E-05 | 2.15E-05 | 27 |