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. 2020 Oct 14;48(20):11394–11407. doi: 10.1093/nar/gkaa837

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Identification of candidate KZFPs binding to imprinted DMRs. (A) Graphical representation of interactions between KZFP and multiple imprinted DMRs. White squares indicate a lack of binding, whereas black squares represent a positive ChIP-seq peak located within the defined imprinted DMR sequence. (B) RNA-seq expression profile for ZNF202, ZNF445 and ZFP57 during human pre-implantation development. (C) Quantitative RT-PCR showing the distribution of expression for the same three KZFPs across different tissues. (D) Western blotting of co-immunoprecipitations between FLAG-ZNF202 and HA-ZNF445 with epitope tagged KAP1.