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. 2020 Oct 23;48(20):11486–11494. doi: 10.1093/nar/gkaa932

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Structural properties of the three types of largest epigenetic domains modeled by HLM. (A) Ensembles of 3D structures of A-23, I-14 and R-11 domains. (B) The mean gyration radius r_g(s) as a function of genomic distance s in log-log scale. (C) Density, , asphericity, and surface roughness S/S₀ of different domains. The density of monomers in I-14 is significantly greater than that in R-11 (Mann–Whitney U test, P < 1 × 10⁻⁵).

Inline graphic — Structural properties of the three types of largest epigenetic domains modeled by HLM. (A) Ensembles of 3D structures of A-23, I-14 and R-11 domains. (B) The mean gyration radius r_g(s) as a function of genomic distance s in log-log scale. (C) Density, , asphericity, and surface roughness S/S₀ of different domains. The density of monomers in I-14 is significantly greater than that in R-11 (Mann–Whitney U test, P < 1 × 10⁻⁵).