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. 2020 Oct 21;64:10.29219/fnr.v64.4364. doi: 10.29219/fnr.v64.4364

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© 2020 Qilin Zhang et al.

This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for any purpose, even commercially, provided the original work is properly cited and states its license.

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Fig. 3 — Effects of WEP1 on the inhibition of tubulin polymerization and the levels of intracellular ROS in H22 cells. (A) Disruption of microtubule network in response to WEP1-treated H22 cells was observed under LSCM. Changes were marked with arrows. (B) (a–e) Representative images of ROS fluorescence in different groups: (a) light microscope image of H22 cells; (b) control; (c–e) cells treated with different concentrations of WEP1 (375, 750, and 1,500 μg/mL). (f) Fluorescence intensity of H22 cells. Values were expressed as means ± SD from three independent experiments. ***P < 0.001 compared with control group.