TABLE 1.

Prostate Cancer Risk Stratification

Risk Level	Very Lowa	Lowa	Intermediateb	Highb	Very Highb
Clinical stage	T1c	T1–T2a	T2b–T2c	T3a	T3b–T4
Gleason score (GS)	≤6	≤6	7	8–10	8–10
Prostate-specific antigen (ng/mL)	<10	<10	10–20	>20	>20
Additional findings	<3 cores positive, ≤50% cancer in each core, PSA density <0.15 ng/mL/g				Primary Gleason pattern 5, >4 cores GS 8–10

^aMust meet all criteria.

^bMeets any criteria.

Adapted from National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology: Prostate Cancer Version 1.2020⁸; Prostate Cancer Patient Guide.⁹