Table 2. Type and Frequency of Illegal Activity Associated With Penalties.
| Companya | No. of penalties | Violation frequency | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Adulterated drugsb | Briberyc | Competitiond | Disclosuree | Environmental violationsf | Financial violationsg | Kickbacksh | Misleading marketingi | Off-label marketingj | Pricingk | Uncategorizedl | ||
| GlaxoSmithKline | 27 | 2 | 2 | 3 | 5 | 3 | 1 | 2 | 5 | 3 | 11 | 1 |
| Pfizer | 18 | 0 | 2 | 0 | 1 | 4 | 0 | 1 | 7 | 5 | 3 | 0 |
| Johnson & Johnson | 15 | 1 | 1 | 0 | 5 | 0 | 0 | 4 | 4 | 9 | 2 | 0 |
| Bayer | 13 | 0 | 0 | 3 | 1 | 4 | 0 | 1 | 3 | 1 | 4 | 0 |
| Schering-Ploughm | 12 | 0 | 0 | 0 | 2 | 0 | 2 | 1 | 1 | 1 | 8 | 0 |
| Bristol Myers Squibb | 12 | 0 | 1 | 4 | 1 | 1 | 2 | 1 | 1 | 2 | 3 | 0 |
| Abbott Laboratories | 11 | 0 | 0 | 2 | 1 | 2 | 0 | 3 | 1 | 1 | 4 | 0 |
| Merck | 11 | 0 | 0 | 0 | 2 | 2 | 1 | 2 | 1 | 2 | 7 | 1 |
| Novartis | 11 | 0 | 1 | 0 | 1 | 0 | 1 | 5 | 0 | 4 | 5 | 0 |
| AstraZeneca | 10 | 0 | 1 | 0 | 1 | 0 | 0 | 4 | 1 | 2 | 6 | 1 |
| Sanofi-Aventis | 10 | 0 | 0 | 2 | 0 | 1 | 0 | 2 | 0 | 0 | 6 | 0 |
| Amgen | 9 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 1 | 3 | 5 | 0 |
| Boehringer Ingelheim | 7 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 1 | 1 | 4 | 0 |
| Eli Lilly | 7 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 7 | 1 | 0 |
| Wyethm | 7 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 4 | 1 | 0 |
| Mylan | 6 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 4 | 0 |
| Forest Laboratoriesm | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 1 | 1 |
| Actavis (Watson) | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 |
| Genzymem | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 0 |
| Allerganm | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Roche Group | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
| Perrigo | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Total | 5 | 9 | 16 | 21 | 21 | 7 | 33 | 32 | 50 | 78 | 4 | |
Biogen, Celgene, Gilead Sciences, and Hospira had no violations in this period.
Manufacturing and distributing adulterated or unapproved drugs.
Bribery to foreign officials, suppliers, or other entities.
Fraudulently delaying market entry of competitors, antitrust, monopoly.
Failure to disclose negative information about a product or about poor drug development.
Violations of environmental regulation(eg, Clean Air Act).
Tax fraud and insider trading.
Offering kickbacks to suppliers or customers to purchase and sell their product(s).
Misleading or deceptive marketing practices.
Advertising a product for uses other than approved by the US Food and Drug Administration.
Overpricing drugs reimbursed or paid for by government, underpaying rebate obligations, fraudulent pricing or billing, or other pricing illegalities.
Violations that do not fit the other reported categories.
Company was acquired before 2016. See footnote d in Table 1.