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. 2020 Nov 17;324(19):1995–1997. doi: 10.1001/jama.2020.18740

Table 2. Type and Frequency of Illegal Activity Associated With Penalties.

Companya No. of penalties Violation frequency
Adulterated drugsb Briberyc Competitiond Disclosuree Environmental violationsf Financial violationsg Kickbacksh Misleading marketingi Off-label marketingj Pricingk Uncategorizedl
GlaxoSmithKline 27 2 2 3 5 3 1 2 5 3 11 1
Pfizer 18 0 2 0 1 4 0 1 7 5 3 0
Johnson & Johnson 15 1 1 0 5 0 0 4 4 9 2 0
Bayer 13 0 0 3 1 4 0 1 3 1 4 0
Schering-Ploughm 12 0 0 0 2 0 2 1 1 1 8 0
Bristol Myers Squibb 12 0 1 4 1 1 2 1 1 2 3 0
Abbott Laboratories 11 0 0 2 1 2 0 3 1 1 4 0
Merck 11 0 0 0 2 2 1 2 1 2 7 1
Novartis 11 0 1 0 1 0 1 5 0 4 5 0
AstraZeneca 10 0 1 0 1 0 0 4 1 2 6 1
Sanofi-Aventis 10 0 0 2 0 1 0 2 0 0 6 0
Amgen 9 0 0 0 0 1 0 3 1 3 5 0
Boehringer Ingelheim 7 0 0 0 0 2 0 1 1 1 4 0
Eli Lilly 7 0 0 0 1 0 0 1 1 7 1 0
Wyethm 7 0 1 0 0 1 0 0 2 4 1 0
Mylan 6 0 0 1 0 0 0 0 1 0 4 0
Forest Laboratoriesm 3 1 0 0 0 0 0 2 0 1 1 1
Actavis (Watson) 2 0 0 0 0 0 0 0 0 0 2 0
Genzymem 2 1 0 0 0 0 0 0 1 2 1 0
Allerganm 1 0 0 0 0 0 0 0 0 1 0 0
Roche Group 1 0 0 0 0 0 0 0 1 1 0 0
Perrigo 1 0 0 1 0 0 0 0 0 0 0 0
Total 5 9 16 21 21 7 33 32 50 78 4
a

Biogen, Celgene, Gilead Sciences, and Hospira had no violations in this period.

b

Manufacturing and distributing adulterated or unapproved drugs.

c

Bribery to foreign officials, suppliers, or other entities.

d

Fraudulently delaying market entry of competitors, antitrust, monopoly.

e

Failure to disclose negative information about a product or about poor drug development.

f

Violations of environmental regulation(eg, Clean Air Act).

g

Tax fraud and insider trading.

h

Offering kickbacks to suppliers or customers to purchase and sell their product(s).

i

Misleading or deceptive marketing practices.

j

Advertising a product for uses other than approved by the US Food and Drug Administration.

k

Overpricing drugs reimbursed or paid for by government, underpaying rebate obligations, fraudulent pricing or billing, or other pricing illegalities.

l

Violations that do not fit the other reported categories.

m

Company was acquired before 2016. See footnote d in Table 1.