Table 3. Pooled Analysis of ARI Use With Fall and Fracture Risk.

Adverse event	ARI groups		Control groups		Pool estimate
	Patients in studies, No.	Patients with adverse events, No.	Patients in studies, No.	Patients with adverse events, No.	Studies, No.	RR (95% CI)	P value
Fall
All grades	6536	525	4846	221	11	1.8 (1.42-2.24)	<.001
Grade ≥3	6536	62	4846	28	11	1.6 (1.27-2.08)	<.001
Fracture
All grades	6536	242	4846	107	11	1.59 (1.35-1.89)	<.001
Grade ≥3	6536	60	4846	23	11	1.71 (1.12-2.63)	.01

Abbreviations: ARI, androgen receptor inhibitor; RR, relative risk.