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The evolutionary conserved hotspot residues determined with ConSurf and KL scores.
| ConSurf Hotspots | Consurf Score | KL Hotspots | KL Score |
|---|---|---|---|
| K390 | −0.390 | K390 | 1.12 |
| V404 | −0.367 | V404 | 1.07 |
| G434 | −0.505 | Y436 | 1.45 |
| Y440 | −0.705 | Y440 | 1.19 |
| N473 | −0.467 | N473 | 1.51 |
| Y475 | −0.705 | Y475 | 1.63 |
| Y481 | 473 | Y481 | 0.72 |
