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. 2020 Nov 4;21(21):8270. doi: 10.3390/ijms21218270

Figure 3.

Figure 3

Reduced serum lactate and bacterial genome number and increased antimicrobial peptide after CD362+ UC-MSC administration at 4 h. Administration of CD362+ UC-MSCs 4 h after CLP induction reduced the lactate measured in serum 48 h after the CLP procedure compared with vehicle (A). Reduction of copies of the 16S fraction of the bacterial genome in serum after CD362+ UC-MSC administration. (B). Reduction of copies of 16S fraction of bacterial genome in peritoneal lavage serum after CD362+ UC-MSC administration (C). Reduction of copies of 16S fraction of bacterial genome in the liver after CD362+ UC-MSC administration (D). Increased concentration of the antimicrobial peptide hepcidin in serum after CD362+ UC-MSC treatment compared with vehicle control (E). Increased presence of the antimicrobial peptide hepcidin in peritoneal lavage in the CD362+ UC-MSC treated group compared with vehicle control (F). Bars represent mean (n = 3/8/8), error bars represent SD. * Statistically significant (p < 0.05) with respect to vehicle group.