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. 2020 Oct 30;25(21):5057. doi: 10.3390/molecules25215057

Table 6.

Lipinski drug-likeness of the target compounds using Molsoft and Swiss ADME software.

Compound Log S a Drug Likeness Model Score Lipinski Violations Bioavailability Score
6a −3.30 −0.23 0 0.55
6b −3.48 0.45 0 0.55
6c −3.53 0.36 0 0.55
6d −3.60 −0.18 0 0.55
6e −3.60 −0.18 0 0.55
6f −3.78 0.31 0 0.55
6g −3.36 −0.21 0 0.55

Log S a: Log of solubility.