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. 2020 Nov 6;21(21):8336. doi: 10.3390/ijms21218336

Figure 6.

Figure 6

Cordycepin decreased FGF9-induced expressions of FGFR1-4 proteins in MA-10 cells. (A) Western blot analysis for the expression of FGFR1, FGFR2, FGFR3 and FGFR4 in MA-10 cells treated without or with FGF9 (50 ng/mL) and different concentrations of cordycepin (0, 25, 50 and 100 µM) for 12, 24, 48 and 72 h. (B–E) The relative expression of (B) FGFR1, (C) FGFR2, (D) FGFR3 and (E) FGFR4 was quantified using ImageJ software by normalization with β-actin. Values are shown as the mean ± SEM, n = 4. p values were calculated using two-way ANOVA with Tukey’s multiple comparisons post-tests. * p < 0.05, compared to the control group (0 ng/mL FGF9) at each dose of cordycepin; § p < 0.05, §§ p < 0.01, §§§ p < 0.001 compared to the group with 0 μM cordycepin and 0 ng/mL FGF9 treatments; ## p < 0.01, ### p < 0.001 compared to the group with 0 μM cordycepin and 50 ng/mL FGF9 treatments.