Table 3.

Clinically relevant SNPs in PI(3)P-binding proteins and ATG9 orthologues.

Gene	Disease	dbSNP rsID
ATG2A	Granuloma formation in Crohn’s disease	rs17146441
ATG2A	Hyperuricemia	rs188780113
ATG2B	Non-muscle invasive bladder cancer	rs3759601
ATG2B	Head and neck squamous cell carcinoma	rs3759601
ATG9B	Coronary artery disease	rs2373929; rs7830
ALFY	Microcephaly	rs1553924800
ALFY	Malignant neoplasm of oropharynx	rs6847067
DFCP1	Tuberculosis	rs2333021
WIPI2	Osteoporosis	rs4720530
WIPI3	Neurodevelopmental disorder	rs786205510; rs1555647262
WIPI4	Rett syndrome	rs886041382; rs886041693
WIPI4	Neurodegeneration with brain iron accumulation	rs886041382
WIPI4	Early-onset epileptic encephalopathy	rs1064793294
WIPI4	β-propeller protein-associated neurodegeneration (BPAN)	rs387907330