Table 2.
Beta-blocker | Control | p-Value | |
---|---|---|---|
(n=572) (%) | (n=578) (%) | ||
Baseline characteristics | |||
Age, year, mean±SD | 61.2±12.4 | 61.4±12.3 | 0.79 |
Male | 451/572 (78.8) | 449/578 (77.7) | 0.63 |
BMI, mean±SD | 27.0±4.2 | 27.2±4.1 | 0.59 |
Hypertension | 249/566 (44.0) | 248/572 (43.4) | 0.83 |
Diabetes | 105/565 (18.6) | 113/575 (19.7) | 0.65 |
Smoking | 260/547 (47.5) | 256/548 (46.7) | 0.79 |
Hyperlipidemia | 197/559 (35.2) | 187/565 (33.1) | 0.45 |
Previous MI | 15/429 (3.5) | 17/445 (3.8) | 0.80 |
Previous PCI | 30/430 (7.0) | 24/446 (5.4) | 0.33 |
Previous CABG | 4/430 (0.9) | 6/446 (1.3) | 0.56 |
Prior beta-blocker use | 54/329 (16.4) | 60/343 (17.5) | 0.71 |
Clinical presentation | |||
Killip class I | 445/472 (94.3) | 447/485 (92.2) | 0.19 |
Killip class II | 24/472 (5.1) | 31/485 (6.4) | 0.39 |
Baseline SBP, mm Hg, mean±SD | 143.8±23.3 | 143.5±23.3 | 0.86 |
Baseline DBP, mm Hg, mean±SD | 87.8±15.8 | 87.8±16.7 | 0.98 |
Pretreatment HR, beat/min, mean±SD | 79.6±14.9 | 80.5±14.9 | 0.30 |
SBP after intervention, mm Hg, mean±SD | 131.0±22.2 | 134.1±25.5 | 0.04 |
DBP after intervention, mm Hg, mean±SD | 79.4±15.1 | 79.8±16.0 | 0.74 |
HR after intervention, beat/min, mean±SD | 72.1±13.1 | 77.9±15.0 | <0.001 |
Hospitalization | |||
Reperfusion time, min, median (IQR) | 182 (137–258) | 183 (130–259) | 0.58 |
Infarct-related artery | |||
LAD | 316/535 (59.1) | 337/540 (62.4) | 0.26 |
LCX | 61/535 (11.4) | 56/540 (10.4) | 0.59 |
RCA | 155/535 (29.0) | 142/540 (26.3) | 0.33 |
No. diseased coronary vessels | |||
1 | 225/427 (52.7) | 254/439 (57.9) | 0.13 |
2 | 124/427 (29.0) | 91/439 (20.7) | 0.005 |
3 | 62/427 (14.5) | 73/439 (16.6) | 0.39 |
Primary PCI during admission | 529/561 (94.3) | 528/569 (92.8) | 0.31 |
CABG during admission | 12/572 (2.1) | 22/578 (3.8) | 0.09 |
Beta-blocker at discharge | 420/515 (81.6) | 413/519 (79.6) | 0.42 |
Admission length, days, median (IQR) | 3.0 (1.0–5.8) | 3.0 (1.0–6.0) | 0.87 |
BMI: body mass index, CABG: coronary artery bypass grafting, DBP: diastolic blood pressure, IQR: interquartile range, LAD: anterior descending artery, LCX: left circumflex artery, MI: myocardial infarction, PCI: percutaneous coronary intervention, RCA: right coronary artery, SBP: systolic blood pressure, SD: standard deviation.