Table 2.
Comparison of the clinical characteristics, preoperative laboratory values, and perioperative data among the 3 groups stratified by the grade of blood loss, as determined by the ATLS hypovolemic shock classification system
| Grade of blood loss | P value | |||
|---|---|---|---|---|
| I < 750 ml (n = 49) | II 750~1500 ml (n = 121) | III> 1500 ml (n = 73) | ||
| Clinical characteristics | ||||
| Age (years) | 32 (19 to 67) | 32 (19 to 59) | 34 (22 to 53) | 0.449 c |
| Male (n, %) | 37 (75.5%) | 110 (90.9%) | 71 (97.3%) | < 0.0001a |
| BMI (kg/m2) | 21.83 (11.87 to 36.73) | 22.76(15.06 to 36.98) | 23.39 (15.22 to 37.11) | 0.078 c |
| Disease duration (years) | 10 (0.5 to 40.3) | 10.5 (1.0 to 30.0) | 14 (0.5 to 34) | 0.114 c |
| Bilateral THA (n, %) | 8 (16.3%) | 84 (69.4%) | 71 (97.3%) | < 0.0001a |
| Hip ROM = 0° (n, %) | 10 (20.4%) | 60 (49.6%) | 51 (69.9%) | < 0.0001a |
| BASRI-hip score of 4 (n, %) | 16 (32.7%) | 68 (56.2%) | 55 (75.3%) | < 0.0001a |
| Preoperative laboratory values | ||||
| Elevated level of ESR (n, %) | 23(46.9%) | 75(62.0%) | 34(46.6%) | 0.058a |
| Elevated level of CRP (n, %) | 31 (63.3%) | 89 (73.6%) | 45 (61.6%) | 0.168a |
| TT (s) | 15.7 ± 0.8 | 16.2 ± 1.0 | 16.2 ± 1.0 | 0.013b |
| APTT (s) | 40.6 ± 4.8 | 41.4 ± 4.7 | 38.7 ± 4.9 | 0.001b |
| PT (s) | 13.6 ± 0.8 | 13.5 ± 0.8 | 13.4 ± 0.9 | 0.206b |
| PT (%) | 93.2 ± 11.3 | 93.9 ± 11.9 | 96.1 ± 12.7 | 0.346b |
| INR | 1.06 ± 0.08 | 1.05 ± 0.08 | 1.03 ± 0.08 | 0.219b |
| Fibrinogen level (g/L) | 4.04 (2.42 to 7.41) | 4.45 (1.90 to 13.10) | 4.06 (1.76 to 6.16) | 0.014c |
| Platelet level (× 109/L) | 270 ± 67 | 289 ± 77 | 249 ± 58 | 0.001b |
| Hb level (g/L) | 127 ± 15 | 131 ± 16 | 140 ± 16 | < 0.0001b |
| Hct (L/L) | 0.386 ± 0.041 | 0.401 ± 0.042 | 0.423 ± 0.041 | < 0.0001b |
| Perioperative data | ||||
| Iliopsoas and adductor release (n, %) | 2 (4.1%) | 23 (19.0%) | 16 (21.9%) | 0.024a |
| Administration of TXA (n, %) | 40 (81.6%) | 77 (63.6%) | 42 (57.5%) | < 0.0001a |
| Chemoprophylaxis of thrombosis (n, %) | 30(61.2%) | 97(80.2%) | 56(76.7%) | 0.033a |
| Operating time (min) | 100 (55 to 250) | 180 (60 to 335) | 210 (70 to 455) | < 0.0001c |
| Autologous transfusion (n, %) | 3 (6.1%) | 30 (24.8%) | 33 (45.2%) | < 0.0001a |
| Allogenic transfusion (n, %) | 37 (75.5%) | 119 (98.3%) | 73 (100%) | N/A |
| ASA class | 0.672a | |||
| 1 | 5 | 6 | 4 | |
| 2 | 40 | 105 | 65 | |
| 3 | 4 | 10 | 4 | |
ATLS Advanced Trauma Life Support, AS ankylosing spondylitis, THA total hip arthroplasty, BMI body mass index, ROM range of motion, BASRI-hip Bath Ankylosing Spondylitis Radiology Hip Index, ESR erythrocyte sedimentation rate, CRP C-reactive protein, TT thromboplastin time, APTT activated partial thromboplastin time, PT prothrombin time, PT% prothrombin activity, INR international normalized ratio, Hb hemoglobin, Hct hematocrit, TXA tranexamic acid, ASA American Society of Anesthesiologists
aChi-square test
bOne-way ANOVA
cWilcoxon rank sum test