Table 3.
Summary of S. haematobium infection by study arm from baseline to Year 5 (9–12 years-old cross-section only)
Variable | Groupa | Total | |||||
---|---|---|---|---|---|---|---|
A1 | A2 | B1 | B2 | C1 | C2 | ||
No. of villages sampled | 38 | 37 | 37 | 38 | 37 | 38 | 225 |
No. tested at baseline | 3461 | 3221 | 3659 | 3671 | 3357 | 3562 | 20,931 |
No. infected at baseline | 129 | 148 | 898 | 825 | 480 | 834 | 3314 |
Prevalence at baseline (%) | 3.7 | 4.6 | 24.5 | 22.5 | 14.3 | 23.4 | 15.8 |
Prevalence of heavy infection at baseline (%) | 0.29 | 0.28 | 1.86 | 1.93 | 0.86 | 2.50 | 1.29 |
No. tested at Year 5 | 3710 | 3648 | 3621 | 3740 | 3689 | 3724 | 22,132 |
No. infected at Year 5 | 22 | 9 | 839 | 503 | 425 | 392 | 2190 |
Prevalence at Year 5 (%) | 0.6 | 0.2 | 23.2 | 13.4 | 11.5 | 10.5 | 9.90 |
Prevalence of heavy infection at Year 5 (%) | 0.13 | 0.03 | 1.77 | 0.64 | 0.57 | 0.83 | 0.66 |
Absolute difference in prevalence at Year 5 and baseline | −3.1 | −4.4 | −1.3 | −9.1 | −2.8 | −12.9 | −5.90 |
Relative difference in prevalence at Year 5 and baseline (% change) | −83.8 | −95.7 | −5.3 | −40.4 | −19.6 | −55.1 | −37.3 |
Village-level arithmetic mean infection intensity at baselineb | 0.77 | 0.52 | 4.11 | 5.1 | 1.78 | 5.37 | 2.94 |
Village-level arithmetic mean infection intensity at Year 5b | 0.14 | 0.05 | 3.62 | 1.39 | 1.37 | 2.18 | 1.46 |
Egg reduction rate (1-Year 5 intensity/baseline) | 0.82 | 0.9 | 0.12 | 0.73 | 0.23 | 0.59 | 0.57 |
Individual-level arithmetic mean infection intensity at baselinec | 0.84 | 0.58 | 4.05 | 4.91 | 1.85 | 5.64 | 2.98 |
Individual-level arithmetic mean infection intensity at Year 5c | 0.14 | 0.05 | 3.61 | 1.38 | 1.37 | 2.2 | 1.46 |
aStudy arms: Low prevalence areas receiving SBT once a year (A1), and twice a year (A2); high prevalence areas receiving SBT once a year (B1), and twice a year (B2); and high prevalence areas receiving CWT once a year (C1), and twice a year (C2)
bVillage-level intensity: This is the mean egg count for all tested 9–12 year-old subjects (including those with zero egg counts), which is a measure of community level contamination potential
cIndividual-level intensity: This is the mean egg count among egg-positive 9–12 year-old subjects, which is an estimate of the intensity of infection among known active cases