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. 2020 Nov 17;12:174. doi: 10.1186/s13148-020-00968-5

Fig. 4.

Fig. 4

Kaplan–Meier curve based on MGMT promoter methylation status determined using frozen samples. For region 1, patients whose tumors were methylated exhibited significantly longer PFS than patients with unmethylated tumors (a). For region 2, patients whose tumors were methylated exhibited significantly longer OS and PFS than patients with unmethylated tumors (b). For region 3, no statistically significant differences in survival were observed between methylated and unmethylated tumors (c)