Table 3.

Duration of the nerve terminal impulses discharge

Terminal type	Indentation	WT	Piezo2cKO
Polymodal nociceptor	100 µm	1.89 ± 0.5 (n = 9)	0.8 (n = 1)
	200 µm	1.9 ± 0.36 (n = 11)	1.55 ± 0.25 (n = 6)
Pure mechano-nociceptor	100 µm	1.9 ± 1.04 (n = 4)	1.3 ± 0.32 (n = 3)
	200 µm	1.2 ± 0.38 (n = 5)	1.7 ± 0.66 (n = 4)
Cold thermoreceptors	100 µm	2.5 ± 0.55 (n = 12)	3.6 ± 0.41 (n = 12)
	200 µm	3.7 ± 0.4 (n = 15)	3 ± 0.28 (n = 19)

Average time (in seconds) of NTIs during the 5 s indentation in the cornea. Data are presented as the mean ± SE. Statistical comparison of NTIs between wild-type and Piezo2^cKO mice was performed using the Student's t test and Mann–Whitney rank-sum test.