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Minimum inhibitory concentrations (MICs) of ampicillin (AMP) and imipenem (IMP) against E. coli MG1655OXA-48 with increasing concentrations of CDD-97 and avibactam.
| MIC (μg/mL) | ||
|---|---|---|
| AMP | IMP | |
| 0 | 512 | 0.625 |
| 4 | 1024 | 0.625 |
| 8 | 512 | 0.3125 |
| 16 | 512 | 0.3125 |
| 32 | 512 | 0.3125 |
| 64 | 512 | 0.3125 |
| 128 | 512 | 0.3125 |
| 256 | 512 | 0.625 |
| [CDD-97] (μg/mL) | ||
| MIC (μg/mL) | ||
| AMP | IMP | |
| 0 | 512 | 0.625 |
| 0.125 | 256 | 0.3125 |
| 0.25 | 128 | 0.3125 |
| 0.5 | 64 | 0.1563 |
| 1 | 32 | 0.1563 |
| 2 | 16 | 0.1563 |
| 4 | 4 | 0.0781 |
| [Avibactam] (μg/mL) | ||
