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. Author manuscript; available in PMC: 2020 Nov 18.
Published in final edited form as: Toxicol Appl Pharmacol. 2020 Sep 12;406:115242. doi: 10.1016/j.taap.2020.115242

Fig. 3.

Fig. 3.

Nitrate/nitrite (Nox) and hydrogen peroxide (H2O2) concentrations in the hearts of rats exposed to air or frack sand dust (FSD) 8 (n = 8 animals/group and at each time point. Exposure to 10 mg/m3 FSD 8 did not affect Nox concentrations in the heart (A). However, H2O2 concentrations were reduced 7 and 27 d after exposure (B; *P < 0.05). There were no treatment-related differences in H2O2 concentrations with exposure to 30 mg/m3 FSD 8. However, H2O2 concentrations were reduced on days 7 and 27, in heart tissue from both air and FSD 8-treated rats (#P < 0.05). N ox concentrations were below the level of detection after exposure to the 30 mg/m3 FSD 8 in all animals.