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. Author manuscript; available in PMC: 2020 Nov 18.
Published in final edited form as: Toxicol Appl Pharmacol. 2020 Sep 12;406:115242. doi: 10.1016/j.taap.2020.115242

Table 3.

Effect of inhalation of 30 mg/m3 FSD 8 on protein concentrations in the kidney.

Protein Air 1 d FSD 8 1 d Air 7 d FSD 8 7 d Air 27 d FSD 8 27 d
μM/μg protein
Calbindin 6.03 ± 2.23 4.97 ± 0.80 7.62 ± 3.61 4.98 ± 0.79 N.D. N.D.
Clusterin 10.51 ± 2.23 7.65 ± 2.61 11.03 ± 2.99 5.41 ± 2.36 N.D. N.D.
GSTα 3.61 ± 1.03 3.83 ± 2.19 5.07 ± 1.91 2.50 ± 0.98 8.59 ± 3.75* 1.28 ± 0.60
IP-10 4.23 ± 1.05 8.83 ± 2.75 9.88 ± 2.49* 4.08 ± 1.02 10.97 ± 3.09 6.54 ± 0.63
KIM-1 10.54 ± 2.73 12.23 ± 5.11 13.18 ± 4.85 5.37 ± 1.19 14.01 ± 5.73 5.24 ± 1.64
OPN 6.48 ± 1.62 6.54 ± 1.39 11.34 ± 2.79* 2.23 ± 0.59 9.05 ± 1.69 7.68 ± 1.68
TIMP-1 9.89 ± 5.36 13.96 ± 9.24 18.64 ± 9.22 7.77 ± 3.70 103.70 ± 35.83 101.42 ± 41.40
VEGF 7.66 ± 2.33 11.96 ± 3.93 11.86 ± 2.82* 5.77 ± 1.58 16.63 ± 3.86 9.06 ± 1.81

FSD 8 vs. air-breathing controls,

*

P ≤ 0.05. N.D., not determined.