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CUL4A-knockdown decreases the expression of MMP2 and MMP9, but increases the expression of p53 in RL95-2 cells. (A) The expression of MMP2 and MMP9 was determined using western blot analysis. (B) Western blotting was used to detect the expression of p53. **P<0.01 vs. shRNA-NC. CUL4A, cullin 4A; MMP, matrix metallopeptidase; shRNA, short hairpin RNA; NC, negative control.
