Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 18;2020:baaa096. doi: 10.1093/database/baaa096

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — SARS-CoV-1–human and SARS-CoV-2–human network. The network includes only interactions between SARS-CoV-1/2 proteins and human targets. Human targets are annotated with level-one Reactome ontology, as shown in legend. Only targets with degree equal or higher than 5 are labeled. Diamond SARS-CoV-1 nodes represent RNA molecules. SARS-CoV-1 specific strains include strains PC4-145, Frankfurt 1, Urbani, TJF, HB and GZ02. Gray nodes are annotated with pathways that are not enriched in this network. In the network, the leftmost arc shows human proteins targeted only by SARS-CoV-1 proteins, the vertical line made of yellow nodes indicates SARS-CoV-1 proteins, the S-shaped arc shows human proteins targeted both by SARS-CoV-1 and SARS-CoV-2 proteins, the vertical line made of red nodes indicates SARS-CoV-2 proteins, and the two right arcs show proteins targeted only by SARS-CoV-2, with the rightmost arc including only proteins with degree equal or higher than 5.