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. 2020 Oct 29;11:574839. doi: 10.3389/fimmu.2020.574839

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Copyright © 2020 Hsu, Lin, Chang, Huang, Huang, Yang, Huang and Lin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TNF-α and lipopolysaccharide (LPS) increase the mRNA expression of iNOS and IL-10 in in vitro-generated human myeloid-derived suppressor cells (MDSCs). (A) Human CD11b⁺CD33⁺ MDSCs generated from PBMCs. (B) The suppressive abilities of human MDSCs. (C) mRNA expression of human MDSCs. *P < 0.05, **P < 0.01, n=5 for each group, Mann-Whitney test. Data were expressed as mean ± SD.