Table 3.
Comparison of baseline characteristics between long- and short-term survivors in non-local group.
| Variable | Long-term survivors (n = 27) | Short-term survivors (n = 34) | P value |
|---|---|---|---|
| Age (years) | 49.3 ± 14.1 | 45.5 ± 12.2 | 0.256 |
| Gender (n, %) | 0.071 | ||
| Male | 23/27 (85.2%) | 22/34 (64.7%) | |
| Tumor size (mm) | 43.0 ± 16.0 | 50.0 ± 16.5 | 0.101 |
| KPS score | 72.9 ± 14.6 | 77.3 ± 12.1 | 0.223 |
| SVZ involvement (n, %) | <0.001 | ||
| Yes | 12/27 (44.4%) | 30/34 (88.2%) | |
| Extent of resection (n, %) | 0.933 | ||
| GTR | 14/27 (51.9%) | 18/34 (52.9%) | |
| Reirradiation (n, %) | 0.003 | ||
| Yes | 19/27 (70.4%) | 11/34 (32.4%) | |
| Re-chemotherapy (n, %) | 0.482 | ||
| Yes | 19/27 (70.4%) | 21/34 (61.8%) | |
| Yes | 2/22 (9.1%) | 5/31 (16.1%) | |
| 1q polysomy (n, %) | 1.0* | ||
| Yes | 2/22 (9.1%) | 3/31 (9.7%) | |
| 19p polysomy (n, %) | 0.092 | ||
| Yes | 8/22 (36.4%) | 5/31 (16.1%) | |
| MGMT promoter (n, %) | <0.001 | ||
| Methylation | 22/27 (81.5%) | 9/34 (26.5%) | |
| TERT promoter (n, %) | 0.383* | ||
| Mutation | 2/7 (28.6%) | 8/15 (53.5%) | |
| P53 expression (n, %) | 0.117 | ||
| Positive | 16/21 (76.2%) | 17/31 (54.8%) | |
| EGFR expression (n, %) | 1.0* | ||
| Positive | 16/21 (76.2%) | 24/31 (77.4%) | |
| Ki-67 index (n, %) | 0.210 | ||
| High | 13/27 (48.1%) | 11/34 (32.4%) |
SVZ, subventricular zone; KPS, Karnofsky performance scale; GTR, gross-total resection; MGMT, O6-methylguanine-DNA-methyltransferase; TERT, telomerase reverse transcriptase; EGFR, epidermal growth factor receptor.
*Fisher’s-Exact Test.
In bold: p value less than 0.05.