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. 2020 Oct 29;11:563044. doi: 10.3389/fimmu.2020.563044

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Copyright © 2020 Xie, Zhang, Shi, Liu, Hu, Qie, Chen, Wang, Wang, Jiang and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single-Cell RNA-Seq Experimental Initial Data Exploration (A) Heatmap of log counts of genes in signature. (B) t-SNE of complete cells isolated from the breast cancer tissue and matched adjacent normal breast tissue. (C) t-SNE of CD45+ cells isolated from the breast cancer tissue and matched normal breast tissue (Left). Pie charts of cell-type fractions for the patient’s tumor-infiltrating immune cells, colored by cell type (Right). (D) The violin plot shows the top 10 most variable genes among different cells in the breast cancer sample.