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. 2020 Oct 29;11:563044. doi: 10.3389/fimmu.2020.563044

Table 1.

Expression of VISTA in breast cancer subpopulations with different clinicopathological characteristics.

Clinicopathological characteristic Group Number VISTA P-value
Pos (n, %) Neg (n, %)
≥55 163 (50.77%) 76 (46.63%) 87 (53.37%)
Age (n = 321) 0.146
<55 158 (49.22%) 61 (38.61%) 97 (61.39%)
Pathological Grade (n = 299) I-II 171 (57.19%) 59 (34.50%) 112 (65.97%)
0.001*
III 128 (42.81%) 69 (53.91%) 59 (46.097%)
T1 95 (31.46%) 38 (40.00%) 57 (60.00%)
T-category
(n = 302)
T2 188 (62.25%) 80 (42.55%) 108 (57.45%) 0.354
T3-T4 19 (6.29%) 11 (57.89%) 8 (42.11%)
N0 189 (81.81%) 89 (47.09%) 100 (52.91%)
Lymph Node Status (n = 231) N1 51 (22.08%) 15 (29.41%) 36 (70.59%)
0.045*
N2 48 (20.78%) 18 (37.50%) 30(62.508%)
N3 7 (3.03%) 5 (71.43%) 2(28.57%)
Luminal 94 (48.45%) 30 (31.91%) 64(68.09%)
Genotype (n = 194) HER 2+ 7 (3.61%) 3 (42.86%) 4(57.14%) <0.001*
Basal-like 93 (47.94%) 64 (68.82%) 29(31.18%)

VISTA, V-domain Ig suppressor of T cell activation; Pos, positive; Neg, negative.

In bold: *p < 0.05, Indicates a statistically significant difference.