Skip to main content
. 2020 Nov 18;15(11):e0242626. doi: 10.1371/journal.pone.0242626

Fig 5. Effects of FGF-2 and/or a soft substratum on TGF-β-induced expression of α-SMA.

Fig 5

Conjunctival fibroblasts were cultured on normal plastic wells or soft substratum wells (64 or 0.2 kPa), and treated with FGF-2 (10 ng/mL) and/or TGF-β2 (2.5 ng/mL) for 48 h, followed by Western blot analysis. The induction of α-SMA by TGF-β2 was decreased on a soft substratum in the softness-dependent manner. FGF-2 suppressed TGF-β-induced α-SMA expression even on the soft substratum. *p < 0.05. Data are shown as the mean ± SE, n = 3.