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. Author manuscript; available in PMC: 2020 Nov 18.
Published in final edited form as: Inhal Toxicol. 2020 Oct 20;32(11-12):403–418. doi: 10.1080/08958378.2020.1834034

Table 6.

Serum chemistry profiles.

Marker Treatment Exposure duration (days) Standard ranges
1 4 8 15 30
CREA (mg/dL) Air 0.13 ± 0.02 0.18 ± 0.02 0.20 ± 0.03 0.21 ± 0.01 0.24 ± 0.02 0.1 – 0.7
ABS 0.10 ± 0.01 0.16 ± 0.02 0.19 ± 0.02 0.19 ± 0.01 0.21 ± 0.02
BUN (mg/dL) Air 15.57 ± 0.65 15.88 ± 0.81 16.63 ± 0.50 14.75 ± 0.96 18.75 ± 0.65 9 – 21
ABS 15.50 ± 1.29 13.88 ± 0.93 18.63 ± 1.09 17.88 ± 0.93* 19.00 ± 0.60
PHOS (mg/dL) Air 9.89 ± 0.31 8.68 ± 0.13 8.41 ± 0.41 7.98 ± 0.21 7.01 ± 0.20 5.8 – 11.2
ABS 10.93 ± 0.49* 9.26 ± 0.23 9.05 ± 0.26 9.51 ± 0.51 * 7.03 ± 0.13
TP Air 5.24 ± 0.16 5.25 ± 0.05 5.23 ± 0.10 5.38 ± 0.06 5.51 ± 0.110 5.3 – 6.9
(g/dL) ABS 5.37 ± 0.10 5.28 ± 0.07 5.24 ± 0.12 5.48 ± 0.14 5.66 ± 0.10
ALB Air 2.80 ± 0.15 2.71 ± 0.04 2.73 ± 0.08 2.74 ± 0.05 2.66 ± 0.05 3.8 – 4.8
(g/dL) ABS 2.85 ± 0.07 2.74 ± 0.05 2.68 ± 0.08 2.86 ± 0.09 2.78 ± 0.05
GLOB Air 2.44 ± 0.02 2.54 ± 0.04 2.50 ± 0.05 2.64 ± 0.05 2.85 ± 0.06 1.5 – 2.8
(g/dL) ABS 2.52 ± 0.03 2.54 ± 0.05 2.56 ± 0.50 2.61 ± 0.07 2.89 ± 0.06
ALT Air 63.57 ± 11.12 55.50 ± 5.05 59.38 ± 6.07 51.63 ± 3.35 54.13 ± 4.23 20 – 61
(U/L) ABS 64.33 ± 5.41 50.25 ± 3.50 61.88 ± 10.95 47.70 ± 7.23 52.50 ± 2.32
ALKP Air 215.86 ± 15 227.25 ± 9 186.88 ± 12 184.13 ± 11 161.25 ± 6 16 – 302
(U/L) ABS 215.17 ± 18 244.38 ± 18 212.38 ± 17 215.17 ± 18 161.25 ± 8
TBIL (mg/dL) Air 0.31 ± 0.14 0.14 ± 0.03 0.13 ± 0.03 0.15 ± 0.04 0.13 ± 0.02 0.1 – 0.7
ABS 0.52 ± 0.11 0.15 ± 0.04 0.15 ± 0.05 0.20 ± 0.08 0.17 ± 0.05
CHOL (mg/dL) Air 50.29 ± 3.00 47.250 ± 1.26 39.38 ± 3.54 43.00 ± 3.99 42.50 ± 4.42 20 – 92
ABS 50.00 ± 3.00 49.57 ± 1.66 36.25 ± 4.86 46.88 ± 2.17 34.75 ± 2.63
CK Air 200.80 ± 65 92.00 ± 7 102.50 ± 21 105.70 ± 12 87.45 ± 7 48 – 340
(U/L) ABS 457.37 ± 64* 120.80 ± 16 118.53 ± 14 108.53 ± 19 99.40 ± 14
LDH Air 326.55 ± 45 388.04 ± 56 322.51 ± 90 558.25 ± 66 335.49 ± 42 167 – 1428
(U/L) ABS 649.80 ± 97* 448.03 ± 76 383.01 ± 65 694.00 ± 25 382.39 ± 34
URIC (mg/dL) Air 1.64 ± 0.67 0.68 ± 0.07 1.33 ± 0.87 0.50 ± 0.08 0.45 ± 0.05 0.8 – 4.4
ABS 1.62 ± 0.43 0.93 ± 0.23 0.80 ± 0.16 1.60 ± 0.59* 0.69 ± 0.08
AST Air 128.00 ± 29 100.25 ± 9 106.00 ± 14 108.25 ± 9 87.38 ± 2 39 – 111
(U/L) ABS 206.00 ± 47* 97.50 ± 8 118.75 ± 19 113.71 ± 13 93.25 ± 7
NH3 (μmol/L) Air 57.71 ± 16.95 31.00 ± 7.04 27.75 ± 4.02 25.88 ± 3.76 19.00 ± 3.13 na
ABS 66.33 ± 14.01 46.13 ± 10.19 34.63 ± 5.23 30.43 ± 5.71 24.50 ± 3.07
CRP (mg/dL) Air 0.17 ± 0.02 0.16 ± 0.02 0.19 ± 0.02 0.20 ± 0.05 0.19 ± 0.03 na
ABS 0.18 ± 0.03 0.16 ± 0.03 0.18 ± 0.03 0.16 ± 0.03 0.16 ± 0.04

Values represents means ± SEMs; n = 8/group/time point.

*

p < 0.05 versus air-control group.