TABLE 1.
Baseline time-invariant recipient and donor characteristics for no gout vs new onset gout cohorts
| Characteristics | No gout | New-onset gout | P |
|---|---|---|---|
| N (%) | 17 126 (100%) | 1399 (100%) | - |
| Mean age at index (y) | 17 126 (49.8) | 1399 (55.1) | <0.0001 |
| Sex (% female) | 7137 (42%) | 462 (33%) | <0.0001 |
| Race (% nonwhite) | 7942 (46%) | 584 (42%) | <0.0001 |
| Median BMI at index (kg/m2) | 17 126 (27.5) | 1399 (29.2) | <0.0001 |
| Mean eGFR at index (mL/min/1.73 m2) | 17 126 (37.0) | 1399 (30.1) | <0.0001 |
| Mean eGFR 6 mo postindex (mL/min/1.73 m2) | 17 126 (63.8) | 1399 (54.3) | <0.0001 |
| Median time on dialysis preindex (mo) | 17 126 (61.3) | 1399 (59.6) | 0.0098 |
| History of hypertension (% yes) | 16 520 (96%) | 1362 (97%) | 0.0791 |
| History of diabetes (% yes) | 8467 (49%) | 745 (53%) | 0.0061 |
| Mean donor age (y) | 17 126 (38.5) | 1399 (41.8) | <0.0001 |
| Donor sex (% female) | 7155 (42%) | 602 (43%) | 0.3614 |
| Donor blood type match (% yes) | 4355 (25%) | 360 (26%) | 0.8021 |
| Delayed graft function w/in 1 wk (% yes) | 4293 (25%) | 418 (30%) | <0.0001 |
| Donor type (% cadaveric) | 15 050 (88%) | 1263 (90%) | 0.0078 |
| CNI type | |||
| Tacrolimus (%) | 16 086 (94%) | 1209 (86%) | <0.0001 |
| Cyclosporine (%) | 552 (3%) | 138 (10%) | |
| Neither (%) | 488 (3%) | 52 (4%) | |
| Acute rejection 6 mo postindex | |||
| Unknown | 302 (2%) | 20 (1%) | 0.0120 |
| No (%) | 15 782 (92%) | 1267 (91%) | |
| Yes (%) | 1042 (6%) | 112 (8%) | |
| Transplant era | |||
| 2008-2010 (%) | 5956 (35%) | 677 (48%) | <0.0001 |
| 2011-2013 (%) | 6279 (37%) | 504 (36%) | |
| 2014-2015 (%) | 4891 (29%) | 218 (16%) | |
BMI, body mass index; CNI, calcineurin inhibitors; eGFR, estimated glomerular filtration rate.