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. 2020 Nov 18;9:e56795. doi: 10.7554/eLife.56795

Figure 3. Development of L2/3 PYR-driven gamma in the mPFC.

(a) ChR2(ET/TC)−2A-RFP-expression in L2/3 PYRs in mPFC after IUE at E15.5 in a coronal slice of a P10 mouse. (b) Characteristic examples of extracellular recordings of LFP and MUA during ramp light stimulations (473 nm, 3 s) of prefrontal L2/3 PYRs at different ages (left) and the corresponding MI of power spectra (right). (c) Z-scored average MI of power spectra for P5-40 mice (n = 115 recordings from 101 mice). (d) Scatter plot displaying stimulus induced peak frequencies during postnatal development for anesthetized (gray, n = 80 recordings/mice) and non-anesthetized mice (green, n = 35 recordings from 21 mice). Marker size displays peak strength. (See Supplementary file 1 for a summary of experimental conditions. See Supplementary file 2 for statistics).

Figure 3—source data 1. Source data for Figure 3d.

Figure 3.

Figure 3—figure supplement 1. Control stimulations of L2/3 PYRs in the mPFC.

Figure 3—figure supplement 1.

(a) Characteristic examples of extracellular recordings of LFP and MUA during control ramp light stimulations (594 nm, 3 s) of mPFC L2/3 PYR at different ages (left) and the corresponding MI of power spectra (right). (b) Z-scored average MI of power spectra for P5-40 mice (n = 111 recordings from 97 mice). (c) Scatter plot displaying stimulus induced peak frequencies across age for anesthetized (gray, n = 76 recordings/mice) and non-anesthetized mice (green, n = 35 recordings from 21 mice). Marker size displays peak strength. (See Supplementary file 1 for a summary of experimental conditions. See Supplementary file 2 for statistics).
Figure 3—figure supplement 1—source data 1. Source data for Figure 3—figure supplement 1c.