Figure 2.

Pathogenesis and correlation between stroke and depression. There are different mechanisms in ischemic stroke [16], ICH [17], SAH [304], and depression [10]. Stroke and depression are associated with oxidative stress. Due to overactive OS activity and impaired anti-OS defenses, 16-30% of ischemic stroke survivors [31, 32], 25% of ICH [33] patients, and 50% of SAH [34] patients may develop depression later, but the age groups vary among studies. Conversely, depression increases the risk of stroke by 33% in patients who experience stressful life events [37].