Table 2.
Multivariate analyses of factors associated with in-hospital mortality between elderly and very elderly patients.
| Factors | Elderly (n=512) | P-value | Very elderly (n=668) | P-value |
|---|---|---|---|---|
| Age | 1.0 (0.9–1.0) | 0.43 | 1.0 (1.0–1.1) | 0.03 |
| Underlying conditions | ||||
| Cancer | 1.4 (0.8–2.3) | 0.26 | 1.4 (0.8–2.3) | 0.20 |
| Bedridden status | 0.8 (0.5–1.4) | 0.49 | 0.9 (0.5–1.6) | 0.65 |
| Do-not-resuscitate status | 4.5 (2.6–7.6) | <0.0001 | 3.1 (2.0–4.8) | <0.0001 |
| Recent admission < 3 months | 0.6 (0.1–2.3) | 0.42 | 3.5 (1.2–10.3) | 0.02 |
| Suspected primary infection site | ||||
| Urinary tract | Ref | 0.20 | Ref | 0.13 |
| Respiratory tract | 1.6 (0.7–3.7) | 0.25 | 1.9 (1.1–3.4) | 0.03 |
| Other known sites | 0.6 (0.1–2.8) | 0.53 | 1.1 (0.4–3.2) | 0.88 |
| Unknown site | 1.0 (0.9–1.0) | 0.43 | 1.5 (0.8–2.9) | 0.26 |
| Etiology of infection | ||||
| Community-acquired | Ref | 0.35 | Ref | 0.11 |
| Healthcare-associated | 0.6 (0.2–1.6) | 0.33 | 0.5 (0.2–1.3) | 0.12 |
| Hospital-associated | 1.9 (0.5–8.0) | 0.37 | 0.4 (0.1–1.1) | 0.07 |
| Vital signs and mental status at time of sepsis suspicion | ||||
| Body temperature (oC) | 0.7 (0.5–0.9) | 0.006 | - | - |
| Systolic blood pressure<100 mmHg | 1.3 (0.8–2.2) | 0.36 | 2.2 (1.4–3.4) | 0.001 |
| Oxygen saturation (%) | 1.0 (0.9–1.0) | 0.13 | 0.97 (0.95–0.99) | 0.002 |
| Glasgow Coma Scale scores | 0.7 (0.7–0.8) | <0.0001 | 0.8 (0.7–0.8) | <0.0001 |
Note: data presented as odds ratio (95% confidence interval).
Ref, reference variable; mmHg, millimeters mercury.