Table 4.
Time (min) | Concentration in tissues (μg/g) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Heart | Liver | Spleen | Lung | Kidney | ||||||
BA-LP | BA | BA-LP | BA | BA-LP | BA | BA-LP | BA | BA-LP | BA | |
5 | 4.413 ± 0.592 | 2.977 ± 0.461 | 21.424 ± 1.190 | 17.025 ± 1.142 | 15.206 ± 1.098 | 3.685 ± 0.602 | 8.296 ± 1.332 | 5.493 ± 0.857 | 92.214 ± 9.867 | 226.611 ± 12.104 |
15 | 5.352 ± 1.047 | 3.871 ± 0.454 | 31.473 ± 1.481 | 18.570 ± 1.634 | 22.711 ± 2.024 | 9.012 ± 0.739 | 15.518 ± 2.138 | 7.590 ± 0.801 | 77.246 ± 6.525 | 53.969 ± 3.301 |
30 | 7.523 ± 0.732 | 2.499 ± 0.323 | 61.790 ± 1.411 | 5.041 ± 0.857 | 25.150 ± 1.384 | 7.494 ± 0.542 | 10.582 ± 1.167 | 3.877 ± 0.653 | 35.562 ± 3.484 | 14.073 ± 1.490 |
60 | 7.510 ± 0.599 | 0.444 ± 0.057 | 50.343 ± 1.814 | 1.931 ± 0.074 | 49.719 ± 2.111 | 5.014 ± 0.251 | 15.530 ± 0.924 | 2.096 ± 0.540 | 17.945 ± 2.196 | 4.636 ± 0.282 |
90 | 5.544 ± 0.551 | 0.385 ± 0.048 | 18.440 ± 1.187 | 1.003 ± 0.042 | 16.511 ± 1.561 | 4.728 ± 0.198 | 8.417 ± 1.110 | 1.326 ± 0.041 | 9.761 ± 0.747 | 3.560 ± 0.200 |
120 | 1.733 ± 0.248 | ND | 2.245 ± 0.181 | 0.451 ± 0.037 | 8.087 ± 0.691 | ND | 3.690 ± 0.823 | 0.702 ± 0.037 | 5.483 ± 0.335 | 2.416 ± 0.181 |
240 | 1.279 ± 0.098 | ND | 4.265 ± 0.466 | ND | 6.552 ± 0.423 | ND | 3.598 ± 0.422 | ND | 4.432 ± 0.289 | ND |
360 | 1.073 ± 0.143 | ND | 3.127 ± 0.502 | ND | 5.894 ± 0.572 | ND | 1.772 ± 0.126 | ND | 3.766 ± 0.303 | ND |
480 | 0.868 ± 0.083 | ND | 1.355 ± 0.057 | ND | 5.251 ± 0.654 | ND | 1.557 ± 0.099 | ND | 3.045 ± 0.151 | ND |
BA-LP and BA were administered by intravenous injection at 100 mg/kg, and data were expressed as mean ± SD (n = 5).