Table 1.
Active force, membrane potential and pHi in endothelium-denuded arteries of 1- to 2-week-old and 2- to 3-month-old rats in normal and Cl−-free PSS.
| Parameters | 2- to 3-month-old rats | 1- to 2-week-old rats | ||
|---|---|---|---|---|
| PSS | Cl−-free PSS | PSS | Cl−-free PSS | |
| Active force, % of maximum | − 0.3 ± 0.4 (7) | 4.2 ± 4.0 (7)# | 1.1 ± 7.7 (10) | 8.1 ± 5.4 (8)# |
| Membrane potential, mV | − 55.7 ± 7.9 (7) | − 34.8 ± 5.5 (7)# | − 44.9 ± 11.2 (10) | − 23.4 ± 5.0 (8)# |
| pHi | 7.44 ± 0.14 (6) | 7.64 ± 0.15 (6)# | 7.39 ± 0.13 (9) | 7.61 ± 0.10 (9) # |
Data are shown as mean ± SD. Numbers in the parentheses indicate the number of rats. Active force values in each of the experimental conditions were calculated as percentage of the maximum obtained during the CRC for methoxamine.
#p < 0.05 Cl−-free PSS versus PSS in the corresponding group (unpaired Student’s t-test).