Table 3.

Statistical Comparisons During the 60-Minute Study Period

	Control Eye IOP	Study Eye IOP	Difference in Mean IOP
	(mm Hg)	(mm Hg)	(Control Eye – Study Eye)
MPD on, no negative pressure	15.5 ± 3.0	15.8 ± 3.6	–0.3 mm Hg (P = 0.37*)
25% Negative pressure	15.6 ± 3.0	13.5 ± 3.4	2.1 mm Hg (P < 0.001)
50% Negative pressure	15.5 ± 2.5	11.5 ± 3.1	4.0 mm Hg (P < 0.001)
75% Negative pressure	15.3 ± 2.4	10.2 ± 2.7	5.1 mm Hg (P < 0.001)

^*This P value is a result of a paired t-test performed at baseline comparing the mean IOP of the study and control eye before application of negative pressure.

The difference between the mean IOPs of the study and control eye was significantly different at all 3 negative pressure settings (P < 0.001) in comparison with baseline.