TABLE 3.

MICs of tested agents against 6 S. maltophilia isolates included in time-kill experiments^a

Isolate	MIC (mg/liter) ofb :
	ATM	ATM-AVI	ATM-CLAV	ATM-REL	ATM-VAB	AMOX-CLAV	CAZ-AVI	IMI-REL	LFX	MER-VAB	TMP-SMZc
SM-1d	≥256	0.5	2	4	8	≥256	32	≥64	>16	32	8
SM-2	≥256	4	8	16	128	≥256	64	≥64	2	≥64	≥16
SM-3	≥256	1	4	4	64	≥256	128	≥64	16	≥64	8
SM-4	≥256	8	≥256	16	≥256	≥256	64	≥64	1	32	≥16
SM-5d	≥256	2	≥256	4	64	≥256	≥256	≥64	8	32	8
SM-6d	≥256	16	128	128	≥256	≥256	≥256	≥64	4	≥64	0.5

^aAVI was tested at 4 mg/liter, CLAV was tested at 2 mg/liter, REL was tested at 4 mg/liter, and VAB was tested at 8 mg/liter.

^bATM, aztreonam; AVI, avibactam; CLAV, clavulanate; REL, relebactam; VAB, vaborbactam; AMOX, amoxicillin; CAZ, ceftazidime; IMI, imipenem; LFX, levofloxacin; MER, meropenem; TMP-SMZ, trimethoprim-sulfamethoxazole.

^cReflects the MIC of the trimethoprim component.

^dSubjected to whole-genome sequencing and quantitative reverse transcriptase PCR analysis.