FIG 1.
(A and B) Day 28 ACM by renal function group in the intention-to-treat (A) and microbiological intention-to-treat (B) populations. Participants were classified by renal function groups as follows: normal renal function (CLCR, ≥80 ml/min), mild RI (CLCR, >50 to <80 ml/min), moderate RI (CLCR, ≥30 to ≤50 ml/min), and severe RI (CLCR, ≥15 to <30 ml/min). Mortality rates (n/N, %) for each renal function group are provided below the graphs, and percentage differences between treatment groups (95% CI) are indicated above each renal function group. ACM, all-cause mortality; CI, confidence interval; CLCR, creatinine clearance; C/T, ceftolozane/tazobactam; MEM, meropenem; n, number of participants who died by day 28; N, number of participants in the treatment group; RI, renal impairment.