FIG 3.

Toxicological evaluation of a gel formulation of occidiofungin following a repeated intravaginal daily dose for 28 days. The effects of treatment with the occidiofungin gel (5 mg/ml) (solid bars) and the gel vehicle control (shaded bars) on the inflammation of vaginal (A) and cervical (B) tissues were compared. Inflammation was scored on a scale of 0 to 3, as follows: 0, negative/normal; 1+, 2+, and 3+, minimal, moderate, and severe inflammation, respectively. There was no statistical difference between the occidiofungin gel and the vehicle control. Error bars indicate standard deviations.