Table 2.

Summary statistics of thresholds of 7-day mortality at 2.5%

	Thresholds	Sensitivity (%)	Specificity (%)	PPV (%)	LR
Respiratory frequency
L 2.5%	≤11/min	2.7 (1.6–4.2)	99.6 (99.5–99.6)	11.1 (6.7–17.0)	6.0 (3.7–9.8)
L 2.5%-U 2.5%	12–18/min
U 2.5%	≥19/min	52.6 (48.8–56.5)	77.3 (76.8–77.7)	4.6 (4.1–5.1)	2.3 (2.2–2.5)
Systolic blood pressure
L 2.5%	≤111 mm Hg	32.2 (28.8–35.7)	88.8 (88.5–89.1)	5.5 (4.9–6.3)	2.9 (2.6–3.2)
L 2.5%-U 2.5%	112–192 mm Hg
U 2.5%	≥193 mm Hg	4.7 (3.3–6.6)	97.4 (97.2–97.6)	3.6 (2.5–4.9)	1.8 (1.3–2.5)
Heart rate
L 2.5%	≤53/min	4.5 (3.1–6.3)	97.8 (97.6–97.9)	4.0 (2.7–5.5)	2.0 (1.4–2.9)
L 2.5%-U 2.5%	54–102/min
U 2.5%	≥103/min	31.8 (28.4–35.3)	83.1 (82.7–83.5)	3.7 (3.2–4.2)	1.9 (1.7–2.1)
Glasgow Coma Scale
2.5%	≤14	53.7 (50.3–57.0)	93.2 (93.0–93.5)	16.8 (15.5–18.3)	7.9 (7.4–8.5)
<2.5%	15
Temperature
L 2.5%	≤35.9°C	27.2 (23.5–31.2)	88.8 (88.4–89.1)	4.0 (3.4–4.7)	2.4 (2.1–2.8)
L 2.5%-U 2.5%	36.0°C–39.8°C
U 2.5%	≥39.9°C	1.1 (0.4–2.4)	99.6 (99.5–99.7)	4.5 (1.7–9.6)	2.7 (1.2–6.2)
Saturation
2.5%	≤96%	52.8 (48.9–56.6)	73.5 (73.1–74.0)	3.8 (3.4–4.2)	2.0 (1.9–2.2)
<2.5%	97%–100%
Creatinine
L 2.5%	≤40 µmol/L	1.7 (0.9–3.0)	99.2 (99.1–99.3)	4.2 (2.2–7.2)	2.0 (1.1–3.6)
L 2.5%-U 2.5%	41–98 µmol/L
U 2.5%	≥99 µmol/L	57.0 (53.3–60.7)	79.1 (78.7–79.6)	5.6 (5.1–6.1)	2.7 (2.6–2.9)
PaO2
L 2.5%	≤9.8 kPa	42.7 (38.2–47.3)	60.8 (59.9–61.7)	4.7 (4.1–5.4)	1.1 (1.0–1.2)
L 2.5%-U 2.5%	9.9–12.3 kPa
U 2.5%	≥12.4 kPa	38.7 (34.3–43.3)	72.9 (72.0–73.7)	6.1 (5.3–7.0)	1.4 (1.3–1.6)
Platelets
L 2.5%	≤164/L	22.4 (19.3–25.8)	88.5 (88.1–88.8)	4.5 (3.8–5.3)	1.9 (1.7–2.3)
L 2.5%-U 2.5%	165–327/L
U 2.5%	≥328/L	23.3 (20.1–26.8)	84.9 (84.4–85.3)	3.6 (3.1–4.2)	1.5 (1.3–1.8)
Bilirubin
<2.5%	<13 µmol/L
2.5%	≥13 µmol/L	41.0 (37.1–44.9)	73.3 (72.8–73.8)	3.3 (2.9–3.7)	1.5 (1.4–1.7)

L, Lower; LR, likelihood ratio; PPV, positive predictive value; U, Upper.