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. 2020 Nov 17;10(11):e038966. doi: 10.1136/bmjopen-2020-038966

Table 1.

Clinical and demographic characteristics of the respondents separated by diabetes type and glycated haemoglobin (HbA1c) level

Variable Type 1 diabetes Type 2 diabetes
All HbA1c <52 mmol/mol HbA1c 52–69 mmol/mol HbA1c ≥70 mmol/mol Standardised mean difference, SMD All HbA1c <52 mmol/mol HbA1c 52–69 mmol/mol HbA1c ≥70 mmol/mol Standardised mean difference, SMD
Number (%) 1373 284 (20.7%) 781 (56.9%) 308 (22.4%) 1353 725 (53.6%) 503 (37.2%) 125(9.2%)
Men, n (%) 690 (50.3) 152 (53.5) 391 (50.1) 147 (47.7) 0.077 822 (60.8) 444 (61.2) 302 (60.0) 76 (60.8) 0.016
Age, years (SD) 48.6 (16.4) 46.9 (17.0) 49.6 (16.1) 47.8 (16.3) 0.113 66.6 (9.1) 66.5 (9.1) 66.9 (9.0) 65.5 (9.7) 0.103
Diabetes duration, years (IQR) 22.0 (12.0–36.0) 19.0 (7.0–32.0) 23.0 (13.0–37.0) 24.0 (13.0–37.0) 0.150 8.0 (4.0–14.0) 6.0 (3.0–11.0) 10.0 (6.0–16.0) 13.0 (6.0–17.0) 0.443
HbA1c mmol/mol (SD) 62 (12.7) 53 (12.5)
BMI, kg/m2 (SD) 26.0 (4.2) 25.2 (3.8) 26.0 (4.2) 26.7 (4.6) 0.239 29.9 (5.3) 29.3 (5.2) 30.3 (5.4) 32.0 (5.5) 0.332
Systolic blood pressure, mm Hg (SD) 127.0 (14.0) 124.8 (14.0) 127.5 (13.8) 127.8 (14.2) 0.145 134.3 (14.3) 134.0 (14.4) 134.5 (13.7) 135.1 (16.5) 0.046
Antihypertensive medication, n (%) 589 (44.7) 99 (36.9) 341 (45.3) 149 (50.2) 0.179 1070 (80.1) 572 (79.6) 404 (81.9) 94 (76.4) 0.091
LDL-cholesterol, mmol/L (SD) 2.4 (0.8) 2.5 (0.8) 2.4 (0.8) 2.5 (0.8) 0.077 2.5 (0.9) 2.5 (0.9) 2.4 (0.9) 2.5 (1.0) 0.026
Lipid-lowering medication, n (%) 642 (48.4) 94 (34.6) 378 (49.8) 170 (57.6) 0.315 900 (68.1) 472 (66.6) 344 (70.1) 84 (69.4) 0.050
Micro-albuminuria, n (%) 132 (10.3) 12 (4.6) 70 (9.5) 50 (17.6) 0.285 194 (18.0) 80 (13.9) 83 (20.1) 31 (34.1) 0.323
Macro-albuminuria, n (%) 31 (2.6) 5 (2.1) 12 (1.8) 14 (5.2) 0.126 52 (5.0) 27 (4.8) 20 (5.1) 5 (6.1) 0.037
Estimated glomerular filtration rate, mL/min (SD) 90.0 (23.5) 90.6 (20.7) 89.1 (22.6) 91.6 (27.7) 0.071 82.3 (23.5) 82.5 (22.3) 81.9 (24.0) 83.4 (27.9) 0.038
Retinopathy, n (%) 875 (65.9) 137 (50.6) 520 (68.2) 218 (74.1) 0.333 327 (29.4) 128 (21.7) 153 (36.3) 46 (47.0) 0.366
Coronary heart disease, n (%) 83 (6.3) 9 (3.3) 53 (7.0) 21 (7.1) 0.113 279 (22.4) 136 (20.2) 111 (24.0) 32 (28.6) 0.130
Stroke, n (%) 48 (3.6) 5 (1.9) 32 (4.2) 11 (3.7) 0.093 96 (7.8) 48 (7.2) 40 (8.9) 8 (7.1) 0.043
Smoker, n (%) 135 (10.1) 14 (5.1) 78 (10.2) 43 (14.4) 0.214 162 (12.9) 79 (11.7) 58 (12.3) 25 (23.1) 0.203
Physical activity, daily, n (%) 359 (27.6) 90 (33.5) 203 (27.2) 66 (23.2) 0.334 426 (34.9) 251 (38.7) 157 (33.9) 18 (16.7) 0.410
Diabetes treatment 0.136 0.813
Diet alone, n (%) 195 (14.4) 172 (23.7) 19 (3.8) 4 (3.3)
Oral hypoglycaemic agent alone, n (%) 718 (53.1) 419 (57.8) 261 (52.0) 38 (30.9)
Insulin alone, n (%) 1335 (97.2) 271 (95.4) 764 (97.8) 300 (97.4) 130 (9.6) 46 (6.3) 63 (12.5) 21 (17.1)
Insulin and oral agent, n (%) 32 (2.3) 9 (3.2) 15 (1.9) 8 (2.6) 266 (19.7) 76 (10.5) 140 (27.9) 50 (40.7)
Insulin pump users, n (%) 356 (26.2) 66 (23.8) 221 (28.5) 69 (22.5) 0.091 2 (0.5) 1 (0.9) 1 (0.5) 0 (0.0) 0.093

BMI, body mass index; LDL, low-density lipoprotein.