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. 2020 Oct 15;22:957–970. doi: 10.1016/j.omtn.2020.10.010

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© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

SNHG10 Promotes OS Progression through FZD3

(A) The proliferation of OS cells after transfection with sh-SNHG10 or co-transfection with FZD3 was evaluated with a CCK-8 assay. (B) The proliferation of OS cells after transfection with sh-SNHG10 or co-transfection with FZD3 was evaluated with a colony-formation assay. (C) The expression of cyclin D1 and E1 in OS cells after transfection with sh-SNHG10 or co-transfection with FZD3 was quantified by western blot. (D) The expressions of E-cadherin, N-cadherin, and vimentin were quantified using western blot after transfection of sh-SNHG10 or co-transfection with FZD3. (E) The migration of OS cells after transfection with sh-SNHG10 or co-transfection with FZD3 was evaluated with a wound-healing assay. (F) The invasion of OS cells after transfection with sh-SNHG10 or co-transfection with FZD3 was evaluated with a transwell assay. In all experiments, bars represent means ± SD from three independent experiments. ∗p < 0.05, ∗∗p < 0.01.