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Structure of PIA. PIA is a homopolymer of N-acetylglucosamine (GlcNAc) residues with β-1–6 linkage. About 15 to 20% of the GlcNAc residues are de-acetylated. In the figure, acetyl groups are in green and the free amino group that results from IcaB-catalyzed deacetylation, which is positively charged at neutral or basic pH, is in red. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)
